Different layers answer different questions
Laboratory and animal research can identify pathways, generate hypotheses, and guide future study. Those findings do not automatically establish a human outcome.
Human evidence depends on the population, formulation, route, comparison, duration, and outcome that were actually studied.
Avoid automatic translation
A biologically plausible mechanism can fail to translate because exposure, formulation, physiology, or study design differs. A careful reference labels mechanistic and preclinical evidence instead of blending it into human conclusions.
Clarity is a design decision
Separating evidence layers in the interface helps readers understand what each source can and cannot support. The distinction should be readable in plain language, not communicated by color alone.